CLSI recommends a minimal citrate tube fill volume of 90%. A validation protocol with clinical and analytical components was set up to determine the tube fill threshold for international normalized ratio of prothrombin time (PT-INR), activated partial thromboplastin time (aPTT) and fibrinogen.
In our study, we validated the minimal citrate tube fill volumes of 73%, 90% and 63% for PT-INR, aPTT and fibrinogen, respectively.
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Validation of the minimal citrate tube fill volume for routine coagulation tests
Source: Wiley
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ReplyDeleteSignificantly Safer Results too. Just playing safe!.. 63 % , 73% & 90% less blood volume than above the mark or exactly @ the mark !
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