Read more:
Breathtaking digital images probe human anatomy like never before
Source: ZME Science
Sunday, September 25, 2016
Blood Drop
Often called a “Digital Age Leonardo da Vinci”, Alexander Tsiaras is a digital innovator, technologist and artist. You might know him from his work that showcases beautiful digital images of the human body, made using cutting edge imaging software along with artsy tweaks. Guided by a passion for the human form and insides, Tsiaras founded the TheVisualMD, an extensive online library that documents human anatomy and illness, as well as Anatomical Travelogue, a company specialized in creating digital works of art that faithfully show the workings of the human body. He also authored a number of well received books like From Conception to Birth: A Life Unfolds, The Architecture and Design of Man and Woman: The Marvel of the Human Body, Revealed, The InVision Guide to a Healthy Heart and The InVision Guide to Sexual Health.
Read more:
Breathtaking digital images probe human anatomy like never before
Source: ZME Science
Read more:
Breathtaking digital images probe human anatomy like never before
Source: ZME Science
Wednesday, September 7, 2016
Sabotaging flagella of bacteria to halt infections
Some bacteria have the ability to ‘swim’ in a controlled fashion through the use of appendages called flagella. Researchers think that disabling these flagella is a key step towards infection control.
Motile bacteria move through the function of flagella. These appendages rotate, which propels an organism forwards. This is a little like the propellers on a boat. Some bacteria have one flagellum, others have many, and some possess none at all. Some of the bacteria regarded as human pathogens have flagella. An example of a flagellate bacterium is the ulcer-causing Helicobacter pylori, which uses multiple flagella to propel itself through the mucus lining to reach the stomach epithelium. Some flagella also serve a function in environmental detection, sensing different conditions and signalling to a bacterium to move to or away from a given niche.
Read more:
Sabotaging bacteria to halt infections
Source: Digital media by Tim Sandle
Motile bacteria move through the function of flagella. These appendages rotate, which propels an organism forwards. This is a little like the propellers on a boat. Some bacteria have one flagellum, others have many, and some possess none at all. Some of the bacteria regarded as human pathogens have flagella. An example of a flagellate bacterium is the ulcer-causing Helicobacter pylori, which uses multiple flagella to propel itself through the mucus lining to reach the stomach epithelium. Some flagella also serve a function in environmental detection, sensing different conditions and signalling to a bacterium to move to or away from a given niche.
Read more:
Sabotaging bacteria to halt infections
Tuesday, September 6, 2016
New finding: Biobank storage time affects blood test results
The amount of time a blood sample has been stored at a biobank may affect the test results as much as the blood sample provider’s age. These are the findings of a new study from Uppsala University, which was published in the scientific journal EBioMedicine. Until now, medical research has taken into account age, sex and health factors of the person providing the sample, but it turns out that storage time is just as important.
They analysed 380 different samples from 106 women between the ages of 29 and 73. To study the impact of storage time, only samples from 50-year-old women were used in order to isolate the time effect. 108 different proteins were analysed. In addition to how long a sample had been frozen, the researchers also looked at what year the sample was taken and the age of the patient when the sample was taken.
‘We suspected that we’d find an influence from storage time, but we thought it would be much less’, says Professor Ulf Gyllensten. ‘It has now been demonstrated that storage time can be a factor at least as important as the age of the individual at sampling.’
Blood from biobanks has been used in research aimed at producing new drugs and testing new treatment methods. The results of this study are important for future drug research, but it is not possible or necessary, to repeat all previous biobank analyses.
Read more:
New finding: Biobank storage time affects blood test results
Source: Uppsala University, Sweden
They analysed 380 different samples from 106 women between the ages of 29 and 73. To study the impact of storage time, only samples from 50-year-old women were used in order to isolate the time effect. 108 different proteins were analysed. In addition to how long a sample had been frozen, the researchers also looked at what year the sample was taken and the age of the patient when the sample was taken.
‘We suspected that we’d find an influence from storage time, but we thought it would be much less’, says Professor Ulf Gyllensten. ‘It has now been demonstrated that storage time can be a factor at least as important as the age of the individual at sampling.’
Blood from biobanks has been used in research aimed at producing new drugs and testing new treatment methods. The results of this study are important for future drug research, but it is not possible or necessary, to repeat all previous biobank analyses.
Read more:
New finding: Biobank storage time affects blood test results
Monday, September 5, 2016
Scientists have finally figured out how cancer spreads through the bloodstream
In what could be a major step forward in our understanding of how cancer moves around the body, researchers have observed the spread of cancer cells from the initial tumour to the bloodstream.
The findings suggest that secondary growths called metastases 'punch' their way through the walls of small blood vessels by targeting a molecule known as Death Receptor 6 (no, really, that's what it's called). This then sets off a self-destruct process in the blood vessels, allowing the cancer to spread.
According to the team from Goethe University Frankfurt and the Max Planck Institute in Germany, disabling Death Receptor 6 (DR6) may effectively block the spread of cancerous cells - so long as there aren't alternative ways for the cancer to access the bloodstream.
Read more:
Scientists have finally figured out how cancer spreads through the bloodstream
Source: ScienceAlert
Image: K. Hodivala-Dilke, M. Stone/Wellcome Images
The findings suggest that secondary growths called metastases 'punch' their way through the walls of small blood vessels by targeting a molecule known as Death Receptor 6 (no, really, that's what it's called). This then sets off a self-destruct process in the blood vessels, allowing the cancer to spread.
According to the team from Goethe University Frankfurt and the Max Planck Institute in Germany, disabling Death Receptor 6 (DR6) may effectively block the spread of cancerous cells - so long as there aren't alternative ways for the cancer to access the bloodstream.
Read more:
Scientists have finally figured out how cancer spreads through the bloodstream
Image: K. Hodivala-Dilke, M. Stone/Wellcome Images
Free sBook - Atlas of Clinical Hematology
This 6th edition of the atlas has integrated the 2001 WHO classification and made use of figures and descriptions to document recently described types of leukemia and lymphoma. The latter include leukemias of dendritic cells, rare lymphomas and persistent polyclonal B lymphocytosis, which takes a special place in the classification.
eBook is available by Alaa M. Khudair
Teacher Assistant – Medical Technology Department – IUG
Open book here (pdf)
Atlas of Clinical Hematology
eBook is available by Alaa M. Khudair
Teacher Assistant – Medical Technology Department – IUG
Open book here (pdf)
Atlas of Clinical Hematology
Sunday, September 4, 2016
Interpreting Plates - Colony Morphology
Bacteria grow tremendously fast when supplied with an abundance of nutrients. Different types of bacteria will produce different-looking colonies, some colonies may be colored, some colonies are circular in shape, and others are irregular. The characteristics of a colony (shape, size, pigmentation, etc.) are termed the colony morphology. Colony morphology is a way scientists can identify bacteria. In fact there is a book called Bergey's Manual of Determinative Bacteriology (commonly termed Bergey's Manual) that describes the majority of bacterial species identified by scientists so far.
Although bacterial and fungi colonies have many characteristics and some can be rare, there are a few basic elements that you can identify for all colonies:
Interpreting Plates
Source: Science Buddies
Although bacterial and fungi colonies have many characteristics and some can be rare, there are a few basic elements that you can identify for all colonies:
- Form - What is the basic shape of the colony? For example, circular, filamentous, etc.
- Elevation - What is the cross sectional shape of the colony? Turn the Petri dish on end.
- Margin - What is the magnified shape of the edge of the colony?
- Surface - How does the surface of the colony appear? For example, smooth, glistening, rough, dull (opposite of glistening), rugose (wrinkled), etc.
- Opacity - For example, transparent (clear), opaque, translucent (almost clear, but distorted vision, like looking through frosted glass), iridescent (changing colors in reflected light), etc.
- Chromogenesis (pigmentation) - For example, white, buff, red, purple, etc.
Interpreting Plates
Neutrophil disorders and their management
Neutrophil disorders are an uncommon yet important cause of morbidity and mortality in infants and children. This article is an overview of these conditions, with emphasis on clinical recognition, rational investigation, and treatment.
Neutrophil disorders
Read more:
Neutrophil disorders and their management
Source: Lakshman and Finn 54 (1): 7 -- Journal of Clinical Pathology
Neutrophil disorders
- Disorders of neutrophil number (neutropenia)
- Disorders of neutrophil function
Read more:
Neutrophil disorders and their management
Source: Lakshman and Finn 54 (1): 7 -- Journal of Clinical Pathology
Cytology Cake
Cytotechnology graduation cake. Cells under a microscope
by Wendy Belgrave
Source: Pinterest,
Wendy Belgrave
by Wendy Belgrave
Wendy Belgrave
Saturday, September 3, 2016
Tick-borne Hemorrhagic Fever Kills Man in Spain
Spanish health authorities said on Thursday they were investigating a possible outbreak of Crimean-Congo hemorrhagic fever (CCHF) which has killed one man and infected a nurse, in the first non-imported case reported in Western Europe.
The 62-year-old man died on Aug. 25 after contracting the CCHF disease during a walk in the Castilla-Leon region, probably from a tick bite he reported - which is one of the main ways it is transmitted - authorities said in a statement.
He also infected the nurse who treated him at a hospital in Madrid and she is now in a stable condition in quarantine at an isolation unit, they said. Authorities are monitoring about 200 other people who had come into contact with the man and nurse.
According to the World Health Organization, CCHF's mortality rate is about 30 percent and it is endemic to Africa, the Balkans and Ukraine, the Middle East and Central Asia.
Read more:
First Local Case of Tick-Borne Disease Kills Man in Spain
Source: Scientific American
Image: ALL OVER PRESS
The 62-year-old man died on Aug. 25 after contracting the CCHF disease during a walk in the Castilla-Leon region, probably from a tick bite he reported - which is one of the main ways it is transmitted - authorities said in a statement.
He also infected the nurse who treated him at a hospital in Madrid and she is now in a stable condition in quarantine at an isolation unit, they said. Authorities are monitoring about 200 other people who had come into contact with the man and nurse.
According to the World Health Organization, CCHF's mortality rate is about 30 percent and it is endemic to Africa, the Balkans and Ukraine, the Middle East and Central Asia.
Read more:
First Local Case of Tick-Borne Disease Kills Man in Spain
Image: ALL OVER PRESS
Paper-based Test Identifies Bogus and Poor Quality Drugs
Counterfeit and substandard medications are a serious problem in the developing world, potentially harming patients who desperately need medical treatment.
Some of these drugs, including the antibiotics ciprofloxacin and ceftriaxone, have been deemed essential by the World Health Organization for the treatment of infections. However, chemists in developing countries often do not have expensive instruments to determine whether a pill is genuine.
Now, a simple paper-based test may be the answer.
Instead of a $30,000 machine, a $1 paper card can test a drug in three minutes to determine whether the medication is inactive or of substandard quality. The tests come in 20-card packets.
Read more:
Paper-based Test Identifies Bogus and Poor Quality Drugs
Source: VOA
Photo: Courtesy of Lieberman and Bliese
Some of these drugs, including the antibiotics ciprofloxacin and ceftriaxone, have been deemed essential by the World Health Organization for the treatment of infections. However, chemists in developing countries often do not have expensive instruments to determine whether a pill is genuine.
Now, a simple paper-based test may be the answer.
Instead of a $30,000 machine, a $1 paper card can test a drug in three minutes to determine whether the medication is inactive or of substandard quality. The tests come in 20-card packets.
Read more:
Paper-based Test Identifies Bogus and Poor Quality Drugs
Photo: Courtesy of Lieberman and Bliese
Finally they have noticed medical laboratory profession
Important work behind the scenes.
Source: The MEDTECH´s Lounge
Influenza D
A new influenza virus that affects cattle has an official name. influenza D. The executive committee of the International Committee of Taxonomy of Virus approved a new genus, Orthomyxovirdae, with a single species, Influenza D virus, because of its distinctness from other influenza types—A, B and C.
The research group showed that influenza D is spread only through direct contact and proved a guinea pig can be used as an animal model to study the virus. Influenza D antibodies have been identified in blood samples from sheep and goats, but the virus does not affect poultry.
Studies are underway to compare the virulence among the bovine and swine influenza D strains and human influenza C using the guinea pig model. If the virus can undergo reassortment in combination with a closely related human influenza virus, it may be able to form a new strain that could pose more of a threat to humans.
Read more:
New Virus Gets Official Name, Influenza D
Source: Newswice
The research group showed that influenza D is spread only through direct contact and proved a guinea pig can be used as an animal model to study the virus. Influenza D antibodies have been identified in blood samples from sheep and goats, but the virus does not affect poultry.
Studies are underway to compare the virulence among the bovine and swine influenza D strains and human influenza C using the guinea pig model. If the virus can undergo reassortment in combination with a closely related human influenza virus, it may be able to form a new strain that could pose more of a threat to humans.
Read more:
New Virus Gets Official Name, Influenza D
Friday, September 2, 2016
Blood Sample Spontaneously Unhemolyzes Because Nurse Asks Nicely
PHILADELPHIA, PA – Sources from a local hospital are reporting a miracle, after a sample received by the laboratory spontaneously unhemolyzed following a discussion with the nurse.
The sample was drawn in the PICU, sent to the lab, and accessioned by medical laboratory technician Nancy Stewart. “After processing the specimen, I noticed the serum was pink, indicating gross hemolysis,” says Stewart. That meant having to call the PICU to request a new sample. Stewart says it’s the best part of her job. “I mean, who wouldn’t love getting yelled at for something they can’t control?”
But luckily for Stewart, PICU nurse Linda Nelson was in a good mood. “Normally, I would be pretty annoyed,” says Nelson. “I would berate the lab tech, accuse her of sabotage, and refuse to draw a new sample. But this time, instead of fighting, I just apologized and politely asked if she could recheck the sample. If it was still hemolyzed, I would gladly obtain a new specimen.”
Read more:
Blood Sample Spontaneously Unhemolyzes Because Nurse Asks Nicely
Source: GomerBlog
The sample was drawn in the PICU, sent to the lab, and accessioned by medical laboratory technician Nancy Stewart. “After processing the specimen, I noticed the serum was pink, indicating gross hemolysis,” says Stewart. That meant having to call the PICU to request a new sample. Stewart says it’s the best part of her job. “I mean, who wouldn’t love getting yelled at for something they can’t control?”
But luckily for Stewart, PICU nurse Linda Nelson was in a good mood. “Normally, I would be pretty annoyed,” says Nelson. “I would berate the lab tech, accuse her of sabotage, and refuse to draw a new sample. But this time, instead of fighting, I just apologized and politely asked if she could recheck the sample. If it was still hemolyzed, I would gladly obtain a new specimen.”
Read more:
Blood Sample Spontaneously Unhemolyzes Because Nurse Asks Nicely
Thursday, September 1, 2016
Blood Test for Colorectal Cancer - Epigenomics AG
Despite recommendations, many people in the target age group are not getting screened for colorectal cancer. However, a new blood-based screening test may help boost those rates because of its simplicity and convenience for the patient. The downside is that the new test is not as sensitive or accurate as a colonoscopy or the other recommended screening approaches.
Approved in April 2016, the Epi proColon (Epigenomics AG) is the first blood-based colorectal screening test to get a thumbs-up from the US Food and Drug Administration (FDA).
This molecular test detects methylated Septin 9 DNA in plasma, which is increased in colorectal cancer and can be found in tumor DNA that has been shed into the bloodstream from both colon and rectal sites. This makes it a differential biomarker for the early detection of colorectal cancer, according to the manufacturer.
Available in Europe since 2012, it is also being marketed in other countries, including China.
Read more:
Blood Test for Colorectal Cancer: The Last Resort?
Source: Medscape
Approved in April 2016, the Epi proColon (Epigenomics AG) is the first blood-based colorectal screening test to get a thumbs-up from the US Food and Drug Administration (FDA).
This molecular test detects methylated Septin 9 DNA in plasma, which is increased in colorectal cancer and can be found in tumor DNA that has been shed into the bloodstream from both colon and rectal sites. This makes it a differential biomarker for the early detection of colorectal cancer, according to the manufacturer.
Available in Europe since 2012, it is also being marketed in other countries, including China.
Read more:
Blood Test for Colorectal Cancer: The Last Resort?
