The E. coli Chromosome Caught in the Act of Replicating

We continue our series of images that have made a difference in microbiology. This one, published by John Cairns in 1963 has earned a most deserved place in textbooks and reviews. It shows a radioautograph of an intact E. coli chromosome in the act of replicating. From this image, Cairns concluded that the E. coli chromosome is:

• a single piece of double stranded DNA, 700-900 μm long, and
• circular.

Read more:
Small Things Considered: Pictures Considered. The E. coli Chromosome Caught in the Act of Replicating

Source: Small Things Considered

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