Wednesday, April 10, 2013

Diagnosis of Bleeding Disorders

When screening for a blood disorder there are five basic tests:
  • Complete Blood Count (CBC) -- measures the amount of hemoglobin, red blood cells, white blood cells and platelets
  • Bleeding Time (surrogate PFA-100) -- measures basic platelet adhesion and aggregation
  • Prothrombin Time (PT) -- measures the clotting ability of extrinsic factors (I, II, V, VII and X)
  • Partial Thrombin Time (PTT) -- measures the clotting ability of intrinsic factors (VIII, IX, XI and XII)
  • Fibrinogen or Thrombin Time (TT) -- measures the level of fibrinogen activity and TT measures whether fibrinogen is inhibited
These tests suggest whether coagulation factor deficiency or thrombocytopenia might be the potential cause of clinical bleeding.
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Diagnosis of Bleeding Disorders




















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2 comments:

  1. RødhetteApril 10, 2013 at 4:43 PM

    If all those tests come up negative and the patient still have an increased bleeding tendency, one might want to consider if the patient has Ehlers Danlos Syndrome (EDS)!

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  2. RAWDA RUTH SARRAILApril 11, 2013 at 9:39 PM

    * This method especially applicable for Neonates & Pedias. ~

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