I have myeloma – please help me understand some terms.

 I think I understand the disease fairly well, but I don’t get how the M spike relates to IgG, IgM, etc. and also kappa and lambda. Also – what are heavy chains and free light chains, and what does it mean if they are polyclonal or monoclonal?

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I have myeloma – please help me understand some terms.

Source: Pathology Student

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