Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Thursday, March 21, 2013

The E. coli Chromosome Caught in the Act of Replicating

We continue our series of images that have made a difference in microbiology. This one, published by John Cairns in 1963 has earned a most deserved place in textbooks and reviews. It shows a radioautograph of an intact E. coli chromosome in the act of replicating. From this image, Cairns concluded that the E. coli chromosome is:
  • a single piece of double stranded DNA, 700-900 μm long, and
  • circular.

Read more:
Small Things Considered: Pictures Considered. The E. coli Chromosome Caught in the Act of Replicating

























Source: Small Things Considered

Art and Science of Laboratory Medicine

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