Duration of storage is dependent on a number of factors, including the management system, supply and demand, and blood type (less common blood types, such as Type AB negative, tend to be stored longer than more common types, particularly Type O). Currently, the Food and Drug Administration (FDA) limits storage duration to a maximum of 42 days, depending on the storage system.
“Stored blood undergoes changes, meaning that transfusion of older red blood cells may result in the delivery of high concentrations of red blood cell components such as hemoglobin, free iron, and red blood cell fragments,” said Colleen G. Koch, MD, MS, MBA, from the Cleveland Clinic in Ohio. “These components may contribute to adverse clinical events observed in a number of investigations.”
“Stored blood undergoes changes, meaning that transfusion of older red blood cells may result in the delivery of high concentrations of red blood cell components such as hemoglobin, free iron, and red blood cell fragments,” said Colleen G. Koch, MD, MS, MBA, from the Cleveland Clinic in Ohio. “These components may contribute to adverse clinical events observed in a number of investigations.”
Read more:
Fresher blood donations may be better for recipients
Source: Science Daily
Image credits: Valentina Petrova/AP
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