Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Friday, February 28, 2014

Monoclonal B-cell lymphocytosis in healthy blood donors

Monoclonal B-cell lymphocytosis (MBL), an essential precursor to chronic lymphocytic leukemia (CLL), is a surprisingly common finding in healthy blood donors, thus raising concerns about the potential risk infusion of these blood products may present to recipients.

MBL is defined as <5000 monoclonal B cells per μL of blood and no lymph node involvement. Low-count MBL (low risk of development of CLL, although risk may be affected by other factors) has <500 cells per μL and clinical MBL (increased risk of CLL) has >500 cells per μL. SLL, small lymphocytic leukemia. Professional illustration by Marie Dauenheimer.

Read more:
Monoclonal B-cell lymphocytosis in donors

Source: Blood
Image credits: ASM image library 


Follow "Art and Science of Laboratory Medicine " on:


https://www.facebook.com/LaboratoryEQAS
https://twitter.com/LaboratoryEQAS
https://plus.google.com/100408138227362094524/posts
http://www.pinterest.com/labmed/medical-laboratory-and-biomedical-science/
http://www.linkedin.com/in/jwahlstedt
http://clinical-laboratory.blogspot.com/feeds/posts/default