Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Monday, April 28, 2014

Neutrophil-Lymphocyte Ratio in Patients With Familial Mediterranean Fever

Blood neutrophil-to-lymphocyte (N/L) ratio is a simple marker of inflammation that can be easily obtained from the differential leucocyte count and has been used to determine disease activity and diagnosis in patients with ulcerative colitis and acute appendicitis.

Familial Mediterranean Fever (FMF) is a recurrent, autosomal recessive autoinflammatory disease characterized with fever and serositis, which is accompanied by pain in the abdominal area, chest, and joints and the disease, is common among Mediterranean communities including Turks, Armenians, Jews, and Arabs.

This study shows that N/L ratio is higher in patients with active FMF compared with FMF patients in remission and controls, and a cut-off value of 2.63 can be used to identify patients with active FMF.

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Neutrophil-Lymphocyte Ratio in Patients With...

Source: PubMed
Image credits: Pathologyoutlines

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