As one of the first research Institutes to take part in the MinION Access Programme (MAP) for portable DNA sequencing, introduced by Oxford Nanopore Technologies, The Genome Analysis Centre (TGAC)’s task force share their experience of the ground breaking trial so far
The team of scientists from TGAC’s Data Infrastructure and Algorithms and Plant and Microbial Genomics groups trialled the miniaturised sensing system by sequencing environmental samples, containing DNA from hundreds or thousands of different organisms.
The team experimented first with a mock community, where they used a simple set of DNA samples from twenty bacteria, created for the Human Microbiome Project. Having developed their experimental and data methods, they then tested real environmental samples sequencing them on the MinION and Illumina platforms for comparison.
The Genome Analysis Centre