The rise of antibiotic-resistant bacteria is a growing problem in the United States and the world. New findings by researchers in evolutionary biology and mathematics could help doctors better address the problem in a clinical setting.
Biologist Miriam Barlow of the University of California, Merced, and mathematician Kristina Crona of American University tested and found a way to return bacteria to a pre-resistant state. In research, they show how to rewind the evolution of bacteria and verify treatment options for a family of 15 antibiotics used to fight common infections, including penicillin. Their work could have major implications for doctors attempting to keep patient infections at bay using "antibiotic cycling," in which a handful of different antibiotics are used on a rotating basis.
Researchers reverse bacterial resistance to antibiotics