Art and Science of Laboratory Medicine. Clinical laboratory and biomedical science related news, abstracts and images for medical laboratory professionals, students and other laboratory geeks.
Art and Science of Laboratory Medicine
Saturday, October 5, 2013
New insights into HIV impact on hematopoiesis
Patients with long-term HIV infection often exhibit multiple hematopoietic syndromes that encompass anemia, granulocytopenia, and thrombocytopenia, suggesting a central deficiency in hematopoiesis. A number of previous studies attempted to delineate the mechanism by which these conditions ensue. However, clear understanding of the impairment mechanism(s) remained an intractable problem because of the paucity of studies using a suitable experimental animal model that closely recapitulates human hematopoiesis during an ongoing HIV infection in vivo.