Art and Science of Laboratory Medicine. Clinical laboratory and biomedical science related news, abstracts and images for medical laboratory professionals, students and other laboratory geeks.
Art and Science of Laboratory Medicine
Saturday, July 20, 2013
A secret to making macrophages
Biologists at the California Institute of Technology (Caltech) have worked out the details of a mechanism that leads undifferentiated blood stem cells to become macrophages -- immune cells that attack bacteria and other foreign pathogens. The process involves an unexpected cycle in which cell division slows, leading to an increased accumulation of a particular regulatory protein that in turn slows cell division further. The finding provides new insight into how stem cells are guided to generate one cell type as opposed to another.