Medical Laboratory and Biomedical Science: Validation of the minimal citrate tube fill volume for routine coagulation tests

Monday, May 13, 2013

Validation of the minimal citrate tube fill volume for routine coagulation tests

CLSI recommends a minimal citrate tube fill volume of 90%. A validation protocol with clinical and analytical components was set up to determine the tube fill threshold for international normalized ratio of prothrombin time (PT-INR), activated partial thromboplastin time (aPTT) and fibrinogen.

In our study, we validated the minimal citrate tube fill volumes of 73%, 90% and 63% for PT-INR, aPTT and fibrinogen, respectively.

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Validation of the minimal citrate tube fill volume for routine coagulation tests

Source: Wiley

Art and Science of Laboratory Medicine

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2 comments:

RAWDA RUTH SARRAIL said...: This comment has been removed by the author.; May 13, 2013 at 11:43 PM
RAWDA RUTH SARRAIL said...: Significantly Safer Results too. Just playing safe!.. 63 % , 73% & 90% less blood volume than above the mark or exactly @ the mark !; June 10, 2013 at 5:21 PM