A 59-year-old woman with disseminated intravascular coagulation was transferred after a dose of growth factor for “leukopenia.” Laboratory studies showed elevated
d-dimer (201 934 ng/mL), with a white blood cell count of 41 000/mm
3 (blasts, 19%; promyelocytes, 37%) and platelets of 49 000/μL, at which time all-
trans-retinoic acid (ATRA) had already been instituted owing to a high suspicion of acute promyelocytic leukemia (APL).
Read more:
Chediak-Higashi–like granules within leukemic promyelocytes
Source: Blood
Image credits:
Blood/ hematology library
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