Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Saturday, March 7, 2015

Normal Pap Smear

Normal cells of the cervix consist basically of squamous, glandular, and metaplastic epithelial cells. The squamous cells line the ectocervix (outer portion) as well as the vagina, and the glandular cells line the endocervix (the inner portion). Squamous metaplastic cells originate from the transformation zone of the cervix where the inner (endocervix) and outer (ectocervix) meet. In order for the cell sample to be satisfactory, endocervical or metaplastic cells must be present as most cervical cancers originate at this highly active transformation zone. Normal appearing endometrial cells may occasionally be seen in association with menses (between Day 1 and12 of the menstrual cycle).

Read more:
Normal Pap Smear, Pap Smear Illustration

Source: Art of cytology

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