Art and Science of Laboratory Medicine. Clinical laboratory and biomedical science related news, abstracts and images for medical laboratory professionals, students and other laboratory geeks.
Art and Science of Laboratory Medicine
Saturday, January 25, 2014
The shape of infectious prions
Prions are unique infective agents -- unlike viruses, bacteria, fungi and other parasites, prions do not contain either DNA or RNA. Despite their seemingly simple structure, they can propagate their pathological effects like wildfire, by "infecting" normal proteins. PrPSc (the pathological form of the prion protein) can induce normal prion proteins (PrPC) to acquire the wrong conformation and convert into further disease-causing agents.