Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Wednesday, July 23, 2014

Frequency Rate of Abnormal Morphologic Shapes of the Erythrocytes upon the Different Types of Anemia

Anaemia is one of the blood diseases that are different forms of blood cells. These shapes indicated the type of disease. It is through the study of 10,000 image from 19 types of anaemia has been drawn 40 shapes of the natural shape of red blood cells. The interesting findings in this study are included Iron deficiency anaemia (IDA) is the most common cases disease; it could reach to 39.5% out of total cases. The most important frequency shapes in IDA are hypocromic microsite (54-62%), Ellipsoids (12-15%), Normocytes (9-11%) and (target, dear drop) (7-9%). Southeast Asian anaemia (SEA) is most common in Malaysia and might be second place after iron deficiency anaemia. The most common shapes of anaemic erythrocytes are stomatocytes (45-64%), kinzocyte (40-45%) and Basophilic (5-8%). Thalassemia showed about 93% of shape of total abnormal RBCs shaped. The majority of abnormal shapes were the hypocromic microsites (54-67%), target (17-21 %) and basophilic cells (8-15%). Megoblastic showed most common shapesof ovalocytosis (41-45%), spherocytosis (29-33%). Haemolytic anaemia is the fourth type of anaemia was shown the erythrocytes look hyporocromic macrosytis, which showed 39% of total abnormal cells. The majority of abnormal shape showed in the Spherocytis (29-35%), Polychromatophilia (13-16%) and Ovalocytosis (9-15%). Red distribution width (RWD) showed highest in IDA, which caused a wide variation in red cell size.

Read more:
Frequency Rate of Abnormal Morphologic Shapes of the Erythrocytes upon the Different Types of Anemia - researchpaper\Frequency-Rate-of-Abnormal-Morphologic-Shapes-of-the-Erythrocytes-upon-the-Different-Types-of-Anemia.pdf


Source: International Journal of Scientific & Engineering Research





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