Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Saturday, April 19, 2014

Erythrocytes with coarse basophilic stippling

 In the latest Case Record of the Massachusetts General Hospital, a 59-year-old man was admitted to the hospital because of fatigue, abdominal pain, new anemia, arthralgias, abnormal liver function, and emotional lability. A peripheral-blood smear showed polychromasia and coarse basophilic stippling of erythrocytes.

Acute abdominal pain has a broad differential diagnosis that includes both intraabdominal and extraabdominal causes. Life-threatening intraabdominal catastrophes, such as gastrointestinal perforation, intestinal infarction, and a ruptured abdominal aortic aneurysm, cause illness within minutes or hours.

Read more:
Case 12-2014 — A 59-Year-Old Man with Fatigue, Abdominal Pain, Anemia, and Abnormal Liver Function 

Source: NEJM

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