Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Wednesday, January 28, 2015

Study Reveals How Listeria Breaches the Placenta

A gut bacterium called Listeria (Listeria monocytogenes), which is often found in soft cheese, is known to present a risk to pregnant women. Listeria uses distinct tactics to breach the intestine and the placenta, using a protein called phosphoinositide-3 kinase (PI3-K).

Listeria has two proteins that help it cross mucosal tissue barriers. Both proteins, called internalins A and B, attach to tissue receptors and are needed for Listeria to invade the placenta, but protein A alone can propel Listeria across the intestine. What underlies these differences has remained unknown.

Read more:
Study Reveals How Listeria Breaches the Placenta

Source: News wice
Image: CDC online

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